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How Malaysian plague fighter Wu Lien-teh laid down lessons for coronavirus

  • A century ago, Wu stopped a pneumonic plague that killed 60,000 in northeast China using preventive measures considered ahead of their time
  • Wu’s lessons still hold relevance in modern medicine today, a Singapore professor says

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Wu Lien-teh helped to contain a plague in Harbin in 1910. Photo: Handout
As the number of coronavirus cases continues to rise in China and elsewhere, the efforts of a Malaysian doctor who ended a pneumonic plague that killed 60,000 in northeast China a century ago bears lessons for the current pandemic, according to a professor in Singapore.
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Wu Lien-teh, a doctor from Penang, was called to Harbin in 1910 to combat a plague, which he found was being transmitted from diseased animals to humans amid a bustling fur trade. More than 95 per cent of infected patients died.

Wu implemented preventive measures to contain the outbreak at a time when antibiotics were not available, including setting up quarantine units, imposing travel bans, and convincing Russian and Japanese authorities to shut railway services to Harbin. Patients who had succumbed to the plague were also cremated in large numbers in hygienic locations.

Wu’s records of his containment efforts – found today at the library of the National University of Singapore (NUS) – formed the basis for accurate clinical decisions in terms of treatment and infection prevention, said Paul Tambyah, President of the Asia Pacific Society of Clinical Microbiology and Infection.

“They also provided valuable information for policymakers who had to make decisions about quarantine, shutting down sections of cities and the allocation of resources,” said Tambyah, a professor of medicine.

The trans-Siberian railway, which carried both passengers and goods for trade to Europe – including fur from Siberian marmots, a species of rodent, harvested in northeast China – had facilitated the transmission of the plague. Someone with the disease could board a train in Harbin and in a matter of days be in Paris or Berlin, Tambyah said.
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“This dramatic escalation of global travel highlighted the perils of emerging infectious diseases,” he said.

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